How long do neutrophils typically live?

Neutrophils typically have a lifespan of about 5 to 7 days. These white blood cells are a crucial component of the immune system and are primarily responsible for responding to infections, particularly bacterial infections. Once neutrophils are activated and migrate to the site of infection, they engage in phagocytosis to engulf pathogens and release enzymes to destroy them. After performing their functions, neutrophils undergo apoptosis (programmed cell death), which helps to maintain homeostasis and prevent excessive inflammation.

The understanding that neutrophils last around 5 to 7 days is significant as it helps to illustrate the dynamic nature of the immune response. Their relatively short lifespan allows for a rapid response to infection and the ability for the body to continuously produce fresh neutrophils.

In contrast, other types of immune cells, such as memory cells or certain lymphocytes, can live for weeks to years, ensuring long-term immunity. A lifespan of 1-3 days is too short for neutrophils given their significant role in the immune response, and a lifespan of 24 hours underestimates their functionality and presence in the bloodstream.