What is the term for insufficient hormone secretion that indicates an endocrine disease?

The term describing insufficient hormone secretion, which is a characteristic of certain endocrine diseases, is hyposecretion. This condition occurs when glands do not produce enough hormones to meet the body's needs, leading to various physiological consequences and symptoms related to the specific hormone that is lacking. For example, in the case of insufficient insulin production in diabetes, it leads to elevated blood glucose levels.

In contrast, normosecretion refers to the normal levels of hormone production, so it does not reflect a pathological condition. Hypersecretion denotes an excess of hormone production, which can lead to conditions like Cushing's syndrome when cortisol levels are too high. The term paracrine describes a form of cell signaling where hormones act locally rather than entering the bloodstream, which does not pertain to insufficient hormone levels. Thus, hyposecretion is the correct answer as it directly relates to a deficiency in hormone production associated with endocrine disorders.