Which hormone inhibits both insulin and glucagon secretion?

Somatostatin is a hormone produced by the delta cells of the pancreas and plays a crucial role in regulating the endocrine system and maintaining glucose homeostasis. It inhibits the secretion of both insulin and glucagon from the pancreatic islets. By doing so, somatostatin helps to balance glucose levels in the blood; when insulin and glucagon secretion are curbed, it prevents extreme fluctuations in blood glucose.

Insulin lowers blood glucose levels by facilitating cellular uptake of glucose, while glucagon raises blood glucose levels by promoting glucose release from the liver. Somatostatin's inhibitory action on these two hormones allows the body to respond to changes in nutrient availability without causing drastic spikes or drops in blood sugar. This feedback mechanism is vital for metabolic stability.