Which type of diabetes is often linked to target cell insensitivity to insulin?

Type 2 diabetes is characterized by insensitivity of target cells to insulin, a condition also known as insulin resistance. In this type of diabetes, the body produces insulin, but the cells do not respond effectively to it, leading to elevated blood glucose levels. This insensitivity can develop due to various factors, including obesity, lack of physical activity, and genetic predisposition. As the condition progresses, the pancreas may struggle to produce enough insulin to overcome this resistance, resulting in more significant metabolic disturbances.

In contrast, Type 1 diabetes involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to little or no insulin production. Diabetes insipidus is unrelated to insulin and is characterized by an inability of the kidneys to conserve water, while pre-diabetes is a condition where blood glucose levels are higher than normal but not high enough for a diagnosis of diabetes. It does not involve the same level of insulin resistance seen in Type 2 diabetes.